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HighRes, Cenevo Partner on Agentic Connected Lab

The companies’ integrated Cellario OS and Mosaic platforms eliminate manual workflow handoffs and improve traceability.

Photo: TippaPatt/Shutterstock.

HighRes and Cenevo have formed a co-marketing partnership designed to accelerate the adoption of connected, artificial intelligence (AI)-ready laboratory infrastructure across the life sciences industry.

The partnership brings together HighRes’ Cellario OS orchestration platform and Cenevo’s Mosaic sample management software to help laboratories coordinate complex workflows across instruments, applications, and data systems with greater reliability and traceability.

Modern life sciences laboratories face mounting pressure to manage increasingly complex samples across dozens of instruments and software systems from different vendors. Each handover between systems introduces risk: manual transcription errors, broken data trails, and compliance gaps. As compound libraries grow and modalities multiply, the cost of these inefficiencies increases dramatically.

“Orchestration and sample management have lived in separate systems for too long, and the gap between them is where errors and lost time accumulate,” HighRes CEO Ira Hoffman said. “By integrating Cellario OS with Mosaic by Cenevo, a sample fulfillment order from the world’s leading sample management software becomes executed work — Cellario OS finds the available resources and runs it. That’s what an execution layer is for.”

Together, Cellario OS and Mosaic address these challenges by creating a seamlessly connected layer across instruments and data, the foundation that makes agentic AI in the lab both practical and safe. Mosaic’s Machine Fulfillment module communicates with Cellario OS before a run begins, passing all order parameters, input and output labware, and transfer specifications upfront. Cellario then orchestrates execution across instruments, from standalone liquid handlers to fully modular Nucleus systems, tracking transfers in real time and feeding results back to Mosaic for full traceability. The result is a hardware-agnostic, resilient workflow where data flows without manual intervention and where AI agents can operate on trusted, structured information.

Together, the integrated solution delivers:

  • Resilience by design — all transfer data is provided upfront and tracked in real time, so runs continue uninterrupted through network or system disruptions.
  • Hardware-agnostic execution — jobs are specified independently of the liquid handler, supporting parallel processing across multiple instruments and intelligent resource planning.
  • Intelligent automation — Cellario templates are automatically selected and refined per job, reducing protocol maintenance burden.
  • Compliance-ready traceability — sample tracking, transfer logging, and instrument data flow back to Mosaic for full regulatory record-keeping.
  • Future-proof architecture — a loosely coupled design that supports emerging capabilities, including agentic interfaces such as the Cellario Lab Assistant communicating with Mosaic via MCP.

“We share a vision for what the connected lab should look like: one where data flows freely across instruments and systems, where AI agents can act on that data with confidence, and where scientists are freed to focus on discovery rather than administration. This partnership is about making data more accessible and more powerful for the whole industry,” Mosaic Product Vice President Alan Parkin stated.

The partnership between HighRes and Cenevo reflects a shared belief that life sciences’ future depends on labs that are automated and connected. Cenevo’s Mosaic is the operational backbone of some of the world’s most complex laboratories, managing samples, workflows, inventory, and compliance across more than 150 device and system integrations. HighRes’ Cellario OS provides the instrument orchestration layer that makes high-throughput automation reliable and reproducible at scale. Together, they give customers something neither can offer alone: a seamlessly connected operating environment where data flows without interruption, scientists stay focused on science, and the infrastructure is ready for the agentic lab of the future.

HighRes designs and builds laboratory automation systems and orchestration software for life sciences organizations. From modular Nucleus hardware to Cellario OS lab orchestration software, HighRes enables scientists to run reproducible, scalable workflows across drug discovery, genomics, synthetic biology, sample management, ELISA, screening, and NGS applications. The company is headquartered in Beverly, Mass., and has European operations in Manchester, U.K.

Cenevo specializes in lab management systems, automation, orchestration, data management and AI technology for life sciences. The company boasts more than 950 customers and 45,000-plus scientist users worldwide. Its team of more than 200 provides customers with global support from its offices in the United Kingdom, United States, Israel, and Poland. Cenevo brings together Mosaic’s sample-centric lab operations with Labguru’s experimental-centric inventory, registration, ELN, and LIMS technology.

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